Thursday, March 29, 2007

Kinda like Ambien.




I'm too lazy to look it up, but Ambien was originally developed as an anti-psychotic. The drug companies behind it though, found out that in lower dosages, it made you sleepy. So it was re-marketed for it's new use.

Funnily enough, I just saw an episode of the Simpsons where Homer is a human test study person. The doctors gave him a pill that was for appetite supression. When a conveyor belt of food scuttled past with food, Homer just sat there.

Doc1: 'Homer, aren't you feeling hungry for any of the food in front of you?'

Homer: 'There's food!!! Where? Oh no! I'm blind!!!!! Wahhh'

Doc 2: 'Who's going to want to take a pill that makes you go blind?'

Doc 1: 'Let marketing figure that out.'

Tests quash new insomnia drug

'Trenton, N.J. - Merck & Co. and its Danish partner, pharmaceutical company H. Lundbeck A/S, are putting to rest development of an insomnia drug that was in the final human testing stage after studies found safety problems, including hallucinations.

The companies said Wednesday they have stopped testing the drug, known by the chemical name gaboxadol, after a three-year partnership. Whitehouse Station, N.J.-based Merck and Copenhagen-based Lund beck had planned this summer to apply for U.S. approval to sell the drug, which likely would have been the first of a new class of sleeping pills.

Anders Gersel Pedersen, Lundbeck's head of drug development, told The Associated Press about a half-dozen tests had shown gaboxadol met goals of inducing deep sleep and leaving patients rested in the morning. Recent tests found problems, though.

Pedersen said one study found limited effectiveness at low doses; another found it waned over time. A third, conducted on drug addicts taking high doses of gaboxadol - required by the Food and Drug Administration because of the risk of addiction with sleeping pills - found more, and more severe, side effects than in a comparison drug.

Those effects included hallucinations, agitation and dissociation from reality, he said.'



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1 Comments:

Blogger lioux said...

One of my dad's nicknames is Homer.

Seriously.

March 30, 2007  

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